Isoxazole to oxazole: a mild and unexpected transformation.
نویسندگان
چکیده
3-Aryltetrahydrobenzisoxazoles prepared en route to the coleophomone natural products and analogues, were found to undergo a remarkable base-mediated rearrangement to 2-aryltetrahydrobenzoxazoles. The scope of this unprecedented, facile transformation was probed: a range of analogues was produced, a mechanism proposed, and an application demonstrated by synthesis of a known herbicidal compound.
منابع مشابه
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ورودعنوان ژورنال:
- Chemical communications
دوره 51 6 شماره
صفحات -
تاریخ انتشار 2015